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            Free, publicly-accessible full text available May 25, 2026
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            Transportation infrastructure experiences distress due to aging, overuse, and climate changes. To reduce maintenance costs and labor, researchers have developed various structural health monitoring systems. However, the existing systems are designed for short-term monitoring and do not quantify structural parameters. A long-term monitoring system that quantifies structural parameters is needed to improve the quality of monitoring. In this work, a novel Transportation Rf-bAsed Monitoring (TRAM) system is proposed. TRAM is a multi-parameter monitoring system that relies on embeddable backscatter-based, batteryless, and radio-frequency sensors. The system can monitor structural parameters with 3D spatial and temporal information. Laboratory experiments were conducted on a 1D scale to evaluate and examine the sensitivity and reliability of the monitored structural parameters, which are displacement and water content. In contrast to other existing methods, TRAM correlates phase change to the change in concerned parameters, enabling long-term monitoring.more » « less
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            ABSTRACT Recent breakthroughs in spatially resolved transcriptomics (SRT) technologies have enabled comprehensive molecular characterization at the spot or cellular level while preserving spatial information. Cells are the fundamental building blocks of tissues, organized into distinct yet connected components. Although many non-spatial and spatial clustering approaches have been used to partition the entire region into mutually exclusive spatial domains based on the SRT high-dimensional molecular profile, most require an ad hoc selection of less interpretable dimensional-reduction techniques. To overcome this challenge, we propose a zero-inflated negative binomial mixture model to cluster spots or cells based on their molecular profiles. To increase interpretability, we employ a feature selection mechanism to provide a low-dimensional summary of the SRT molecular profile in terms of discriminating genes that shed light on the clustering result. We further incorporate the SRT geospatial profile via a Markov random field prior. We demonstrate how this joint modeling strategy improves clustering accuracy, compared with alternative state-of-the-art approaches, through simulation studies and 3 real data applications.more » « less
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